1. Albertine KH, Soulier MF, Wang Z et al. Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome. Am J Pathol 2002; 16: 1783-1796.
2. Amato MB, Barbas CS, Medeiros DM et al. Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 1998; 338: 347-354.
3. Carlon GC, Combs AH. Mechanical ventilation and the diseased lung. Crit Care Med 2000; 28: 2662-2664.
4. Cohen J. The immunopathogenesis of sepsis. Nature 2002; 420: 885-891.
5. Dos Santos CC, Slutsky AS. Mechanisms of ventilator-associated lung injury. J Appl Physiol 2000; 89: 1645-1655.
6. Esteban A, Anzueto A, Alia A et al. How is mechanical ventilation employed in the intensive care unit? Am J Respir Crit Care Med 2000; 161: 1450-1458.
7. Ferring M, Vincent JL. Is outcome from ARDS related to the severity of respiratory failure? Eur Respir J 1997; 10: 1297-1300.
8. Frank JA, Matthay MA. Science review: mechanism of ventilator-induced lung injury. Critical Care 2003; 7: 233-241.
9. Gajic O, Frutos-Vivar F, Esteban A et al. Ventilator settings as a risk factor for acute respiratory distress syndrome in mechanically ventilated patients. Intensive Care Med 2005; 31: 893-895.
10. Gattinoni L, Chiumello D, Cressoni M et al. Pulmonary computed tomography and adult respiratory distress syndrome. Swiss Med Wkly 2005; 135: 169-174.
11. Gattinoni L, Pesenti A. The concept of “baby lung”. Intensive Care Med 2005; 31: 776-784.
12. Guery BPH, Welsh DA, Viget N et al. Ventilation-induced lung injury is associated with an increase in gut permeability. Shock 2003; 19: 559-563.
13. Haitsma JJ, Uhlig S, Göggel R et al. Ventilator-induced lung injury leads to loss of alveolar and systemic compartmentalization of tumor necrosis factor-alpha. Intensive Care Med 2000; 26: 1515-1522.
14. Henzler D, Pelosi P, Dembinski R et al. Respiratory compliance but not gas exchange corelates with changes in lung aeration after a recruitment maneuver: an experimental study in pigs with saline lavage lung injury. Crit Care 2005; 9: R471-R482.
15. Chastre J, Trouillet JL, Vuagnat A et al. Nosocomial pneumonia in patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 1998; 157: 1165-1172.
16. Imai Y, Parodo J, Kajikawa O et al. Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome. JAMA 2003; 289: 2104-2112.
17. Lassen HC. A preliminary report on the 1952 epidemic of poliomyelitis in Copenhagen with special reference to the treatment of acute respiratory insufficiency. Lancet 1953; 1: 37-41.
18. Lichtwarck-Aschoff M, Mols G, Hedlund AJ et al. Compliance is nonlinear over tidal volume irrespective of positive end-expiratory pressure level in surfactant-depleted piglets. Am J Respir Crit Care Med 2000; 162: 2125-2133.
19. Matute-Bello G, Liles WC, Steinberg KP et al. Soluble Fas ligand induces epithelial cell apoptosis in humans with acute lung injury (ARDS). J Immunol 1999; 163: 2217-2225.
20. Mead J, Takishima T, Leith D et al. Stress distribution in lungs: a model of pulmonary elasticity. J Appl Physiol 1970; 28: 596-608.
21. Meduri GU. Clinical review: A paradigm shift: the bidirectional effect of inflammation on bacterial growth. Clinical implications for patients with acute respiratory distress syndrome. Crit Care 2002; 6: 24-29.
22. Munford RS, Pugin J. Normal responses to injury prevent systemic inflammation and can be immunosuppressive. Am J Respir Crit Care Med 2001; 163: 316-321.
23. Murphy DB, Cregg N, Tremblay LN et al. Adverse ventilatory strategy causes pulmonary-to-system translocation of endotoxin. Am J Respir Crit Care Med 2000; 162: 27-33.
24. Nagel T, Resnick N, Dewey CF et al. Vascular endothelial cells respond to spatial gradients in fluid shear stress by enhanced activation of transcription factors. Arterioscler Thromb Vasc Biol 1999; 19: 1825-1834.
25. Parker JC, Hernandez LA, Peevy KJ. Mechanisms of ventilator-induced lung injury. Crit Care Med 1993; 21: 131-143.
26. Pinski MR. Sepsis and Inflammation: The process of dying from critical care. In: Vincent JL (eds). Yearbook of Intensive care Medicine 1996; München: Springer-Verlag 1996, 3-10.
27. Plötz FB, Vreugdenhil HA, Slutsky AS et al. Mechanical ventilation alters the immune response in ventilated children without lung pathology. Int Care Med 2002; 28: 486-492.
28. Plötz FB, Slutsky AS, van Vught AJ et al. Ventilator-induced lung injury and multiple system organ failure: a critical review of facts and hypotheses. Int Care Med 2004; 30: 1865-1872.
29. Pugin J, Dunn I, Jolliet P et al. Activation of human macrophages by mechanical ventilation in vitro. Am J Physiol 1998; 275: L1040-L1050.
30. Radford EP. Static mechanical properties of mammalian lungs. In: Fenn WO, Rahn H (eds). Handbook of Physiology. Section 3: Respiration, Vol. I. Washington (DC): American Physiological Society; 1964, Vol. 1/3: 429-449.
31. Ranieri VM, Suter PM, Tortorella C et al. Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: a randomized controlled trial. JAMA 1999; 282: 54-61.
32. Ranieri VM, Giunta F, Suter PM et al. Mechanical ventilation as a mediator of multisystem organ failure in acute respiratory distress syndrome JAMA 2000; 284: 43-44.
33. Rubenfeld GD, Caldwell E, Hudson L. Publication of study results does not increase use of lung protective ventilation in patients with acute lung injury. Am J Respir Crit Care Med 2001; 163: A295
34. Schultz MJ, Haitsma JJ, Slutsky AS et al. What tidal volumes should be used in patients without acute lung injury? Anesthesiology 2007; 106: 1226-1231.
35. Suter PM, Fairley B, Isenberg MD. Optimum end-expiratory airway pressure in patients with acute pulmonary failure. N Engl J Med 1975; 292: 284-289.
36. Tremblay LN, Slutsky AS. Ventilator-induced injury: from barotrauma to biotrauma. Proc Assoc Am Physicians 1998; 110: 482-488.
37. Tremblay LN, Miatto D, Hamid Q et al. Injurious ventilation induces widespread pulmonary epithelial expression of tumor necrosis factor-alpha and interleukin-6 messenger RNA. Crit Care Med 2002; 30: 1693-1700.
38. Tremblay LN, Valenza F, Ribeiro SP et al. Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model. J Clin Invest 1997; 99: 944-952.
39. Vincent JL, Bihari D, Suter PM et al. The prevalence of nosocomial infection in intensive care units in Europe: result of the European Prevalence of Infection in Intensive Care (EPIC) Study. JAMA 1995; 274: 639-644.
40. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 2000; 342: 1301-1308.
41. Verbrugge SJ, Sorm V, van’t Veen A et al. Lung overinflation without positive end-expiratory preassure promotes bacteriemia after experimental Klebsiella pneumoniae inoculation. Int Care Med 1998; 24: 172-177.
42. Villar J. Ventilator or physician-induced lung injury? Minerva Anestesiol 2005; 71: 255-258.
43. Weinert CR, Gross CR, Marinelli WA Impact of randomized trial results on acute lung injury ventilator therapy in teaching hospitals. Am J Respir Crit Care Med 2003; 167: 1304-1309.
44. Wolthuis E, Spronk P, Kuiper M et al. Dutch intensivists do not use small tidal volume in mechanical ventilation. Critical Care 2004; 8(Suppl 1): P26.
45. Young MP, Manning HL, Wilson DL et al. Ventilation of patients with acute lung injury and acute respiratory distress syndrome: has new evidence changed clinical practice? Crit Care Med 2004; 32: 1260-1265.