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Internal Medicine

A present view on ivabradine in the therapy of cardiovascular diseases

A present view on ivabradine in the therapy of cardiovascular diseases

Cardiovascular illnesses belong to diseases with the highest prevalence. They are also the most predominant reason of death in the vast majority of European countries. Hence...

Issue: 5/2017

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Osteoprotective therapy with bisphosphonates or denosumab in patients with multiple myeloma: benefit and risks

Osteoprotective therapy with bisphosphonates or denosumab in patients with multiple myeloma: benefit and risks

Bisphosphonates have been used during the complete treatment of multiple myeloma for more than twenty years. They slow osteolysis and thereby contribute to the improvement of...

Authors: Zdeněk Adam, Jan Straub, Marta Krejčí, Luděk Pour, Dagmar Brančíková, Lenka Ostřížková, Viera Sandecká, Martin Štork
Issue: 5/2017

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Novelties in the treatment of heart failure

Novelties in the treatment of heart failure

Heart failure (HF) is a complex clinical syndrome which is manifested by characteristic symptoms and objective signs of cardiac insufficiency. The incidence of HF, particularly...

Authors: Filip Souček, Jan Novak
Issue: 4/2017

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AT1 blockers – comparability with ACE inhibitors

AT<sub>1</sub> blockers – comparability with ACE inhibitors

The reduction in overall mortality, cardiovascular mortality and the occurrence of myocardial infarction in patients treated with AT1 blockers is comparable with the use of ACE...

Issue: 4/2017

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How to create cooperative patient for antihypertensive and hypolipidemic therapy

How to create cooperative patient for antihypertensive and hypolipidemic therapy

Patient drug adherence is a major problem especially in the prevention of cardiovascular disease of atherosclerotic origin. On one hand, antihypertensive drugs and hypolipidemic...

Issue: 4/2017

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Relapsing autoimmune pancreatitis type 1: case report

Relapsing autoimmune pancreatitis type 1: case report

Autoimmune pancreatitis (AIP) is a rare form of chronic pancreatitis, classified into 2 subtypes – AIP type 1 and AIP type 2. We present a case of a 31-years-old female...

Authors: Alena Ondrejková, Bohuslav Kianička, Hana Nechutová, Lukáš Hruška, Ivo Novotný, Miroslav Souček
Issue: 4/2017

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Indeterminate cell histiocytosis - disappearance of skin infiltration following electron beam therapy and an application of 2-chlorodeoxyadenosine: case report

Indeterminate cell histiocytosis - disappearance of skin infiltration following electron beam therapy and an application of 2-chlorodeoxyadenosine: case report

Indeterminate cell histiocytosis is a rare disease belonging to the group of malignant histiocytic diseases. The disease predominantly affects the skin. The disease appeared in...

Authors: Zdeněk Adam, Marta Ježová, Pavel Šlampa, Leoš Křen, Vladimír Vašků, Renata Koukalová, Zdeněk Řehák, Luděk Pour, Marta Krejčí, Zdeněk Král, Jiří Mayer
Issue: 4/2017

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Diabetic foot syndrome: importance of calf muscles MR spectroscopy in the assessment of limb ischemia and effect of revascularization

Diabetic foot syndrome: importance of calf muscles MR spectroscopy in the assessment of limb ischemia and effect of revascularization

Aim: The standard method for assessment of effect of revascularization in patients with diabetic foot (DF) and critical limb ischemia (CLI) is transcutaneous oxygen pressure...

Authors: Andrea Němcová, Michal Dubský, Alexandra Jirkovská, Petr Šedivý, Miloslav Drobný, Milan Hájek, Monika Dezortová, Robert Bém, Vladimíra Fejfarová, Anna Pyšná
Issue: 4/2017

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Issue No.: 4 / 2017

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