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Internal Medicine

Epicardial fat and osteoprotegerin – does a mutual relation exist? Pilot study

Epicardial fat and osteoprotegerin – does a mutual relation exist? Pilot study

Introduction: Epicardial fat (EPI) plays important role in development of metabolic and cardiovascular diseases. According to population studies EPI represents independent risk...

Authors: Markéta Sovová, Eliška Sovová, Jana Zapletalová, Markéta Kaletová, David Stejskal, Milan Sova, Michal Konečný, Vlastimil Procházka, Drahomíra Vrzalová, Lea Zarivnijová
Issue: 4/2018

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Impact of surgery on quality of life in Crohn´s disease patients: final results of Czech cohort

Impact of surgery on quality of life in Crohn´s disease patients: final results of Czech cohort

Introduction: Crohn’s disease (CD) belongs to chronic diseases that highly affect the patient´s quality of life (QoL). The effect of the disease and impairment of QoL in CD...

Authors: Lumír Kunovský, Ladislav Mitas, Filip Marek, Jiri Dolina, Karolina Poredska, Lenka Kucerova, Klara Benesova, Zdeněk Kala
Issue: 4/2018

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Effectiveness and safety of lixisenatide for treatment of diabetes in the real world: data from the Monitoring Registry in a Real-Life Cohort in the Czech and Slovak Republic

Effectiveness and safety of lixisenatide for treatment of diabetes in the real world: data from the Monitoring Registry in a Real-Life Cohort in the Czech and Slovak Republic

Introduction: GLP1 receptor agonist lixisenatide has demonstrated its efficacy in numerous clinical trials, nevertheless its real-life effectiveness data is limited.Aim: To...

Authors: Martin Haluzík, Alena Adamíková, Milan Běhunčík, Marek Macko, Radka Štěpánová
Issue: 4/2018

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Diagnosis of MODY – brief overview for clinical practice

Diagnosis of MODY – brief overview for clinical practice

Maturity Onset Diabetes of the Young (MODY) comprises inherited forms of diabetes mellitus caused by the mutations in the genes involved in the development, differentiation and...

Authors: Jana Urbanová, Ludmila Brunerová, Jan Brož
Issue: 4/2018

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Rotational thromboelastometry in therapy of life threatening bleeding

Rotational thromboelastometry in therapy of life threatening bleeding

Bleeding and coagulopathy is a common problem in the fields of internal medicine. In case of life-threatening bleeding, rotational thromboelastometry (ROTEM) has critical role...

Issue: 4/2018

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Drug and herbal hepatotoxicity: an overview of clinical classifications

Drug and herbal hepatotoxicity: an overview of clinical classifications

Drug induced liver injury (DILI) is often underdiagnosed disease with increasing incidence. In developed countries it belongs to the leading causes of acute liver failure. Risk...

Authors: Mária Szántová, Jozef Sedlačko, Martina Jakabovičová
Issue: 4/2018

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Dyslipidemia and hypertension – what to worry about more?

Dyslipidemia and hypertension – what to worry about more?

Dyslipidemia is present in every other patient with arterial hypertension. With increasing blood pressure and cholesterol levels, the risk of cardiovascular events increases...

Issue: 4/2018

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A consensual therapeutic recommendation for type 2 diabetes mellitus by the Slovak Diabetes Society (2018)

A consensual therapeutic recommendation for type 2 diabetes mellitus by the Slovak Diabetes Society (2018)

Type 2 diabetes mellitus is a heterogeneous medical condition involving multiple pathophysiological mechanisms. Its successful treatment requires an individualized approach and...

Authors: Emil Martinka, Vladimír Uličiansky, Marián Mokáň, Ivan Tkáč, Peter Galajda, Silvia Dókušová, Zbynek Schroner
Issue: 4/2018

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Issue No.: 4 / 2018

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