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Internal Medicine

Medication adherence to non-vitamin K antagonist oral anticoagulants at non-valvular atrial fibrillation – the literature review

Medication adherence to non-vitamin K antagonist oral anticoagulants at non-valvular atrial fibrillation – the literature review

Medication adherence is a complex problem reflecting variations in terms of medication taking behavior. It is essential in maximizing of the effect and risk minimization of the...

Authors: Simona Dvořáčková, Kateřina Ládová, Josef Malý, Jozef Kolář, Miroslav Penka
Issue: 10/2017

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Surgical treatment of aortic root aneurysm: comparison of Bentall procedure and David reimplantation of aortic valve

Surgical treatment of aortic root aneurysm: comparison of Bentall procedure and David reimplantation of aortic valve

Introduction: The aortic root aneurysm is associated with a more frequent occurrence of aortic dissection and development of aortic regurgitation. The aim of this study was to...

Authors: Jiří Ničovský, Jiří Ondrášek, Jan Černý, Daniela Žáková, Petr Němec
Issue: 10/2017

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Treatment strategy of type 2 diabetes used in Czech Republic after metformin therapy failure

Treatment strategy of type 2 diabetes used in Czech Republic after metformin therapy failure

Introduction: Type 2 diabetes is an enormous medical problem caused by increasing prevalence of the disease and increasing prevalence of severe chronic complications of diabetes...

Authors: Štěpán Svačina, Petra Ovesná, Matyáš Kuhn, Martina Nováčková
Issue: 10/2017

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Issues related to secondary osteoporosis associated with growth hormone deficiency in adulthood

Issues related to secondary osteoporosis associated with growth hormone deficiency in adulthood

Growth hormone (GH) increases linear bone growth through complex hormonal reactions, mainly mediated by insulin like growth factor 1 (IGF1) that is produced mostly by...

Authors: Martin Kužma, Peter Jackuliak, Zdenko Killinger, Peter Vaňuga, Juraj Payer
Issue: 10/2017

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COSYREL – an efficient fixed combination for treatment of hypertension, stable ISHD and heart failure

COSYREL – an efficient fixed combination for treatment of hypertension, stable ISHD and heart failure

Fixed combinations of two or three drugs are being frequently used in cardiovascular diseases. This approach markedly increases adherence of the patients to prolonged therapy...

Issue: 10/2017

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Endocrine orbitopathy: the present view of a clinical endocrinologist

Endocrine orbitopathy: the present view of a clinical endocrinologist

Graves’ orbitopathy (GO) occurs in 25–50 % cases of Graves’ disease. Only in 5 % of patients the eye threatening GO is present. About 5–10 % and 10 % cases are present...

Issue: 10/2017

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Faster Insulin Aspart – a new prandial insulin analogue

Faster Insulin Aspart – a new prandial insulin analogue

Preventing postprandial blood glucose excursions is one of the most challenging aspects of achieving adequate control, especially in patients with better long-term compensation...

Issue: 10/2017

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Osteoarthritis as part of metabolic syndrome?

Osteoarthritis as part of metabolic syndrome?

Osteoarthritis (OA) is the most frequent joint disease, whereas etiopathogenesis of OA is not entirely clarified. It is a heterogeneous disorder and genetic as well as...

Issue: 10/2017

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Issue No.: 10 / 2017

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